In Vitro Hepatic Models for ADME-Tox Research
Moldoc Biotech Private Limited (MBPL) (now officially a distributor of MileCell Bio, USA/China) is dedicated to offering primary hepatocytes, liver microsomes, and liver fractions-related products.
Why MileCell Bio Cryopreserved Animal Hepatocytes?
Primary
Hepatocytes: In Vitro Hepatic Models for ADME-Tox Research
Primary hepatocytes are indispensable in drug discovery and preclinical research, serving to assess drug metabolism, toxicity, and efficacy. These cells provide a reliable model for evaluating the pharmacokinetic and toxicological profiles of new compounds, enabling researchers to predict human responses and optimize drug safety and effectiveness.
Advantages
of MileCell Bio Cryopreserved Animal Hepatocytes:
Exceptional
Viability and Thorough Characterization
Demonstrate exceptional viability and undergo thorough characterization, including assessment of thawed cell viability, plateability, reproducibility, and the activity of Phase I and Phase II drug-metabolizing enzymes.
Prequalified
and Ready-to-Use Form
All MileCell Bio cryopreserved animal hepatocytes are prequalified and provided in a ready-to-use format, suitable for suspension or plated assays.
HIGH POST-THAW VIABILITY
All MileCell Bio cryopreserved animal hepatocyte lots undergo pre-qualification to ensure a post-thaw viability of over 70% before percoll purification.
Consistent Viability Over Incubation Period
These lots demonstrate consistent viability over a 4-hour incubation period.
Ideal for Short-Term Studies
They are primarily used for compound stability and metabolite formation studies, making them well-suited for short-term investigations typically lasting 4-6 hours.
High Confluence After Thawing and Plating
MileCell Bio cryoplateable animal hepatocyte lots exhibiting a confluence of over 80% on day 2 after cell thawing and plating.
